Applied Microspheres

Particle Size Standards and Count Controls meeting the criteria obligatory for instrument calibration under ISO/IEC 17025 and as such meet the highest international metrological standard available.

We are at Analytica

Hall / stand: A2 / 524A

April 09–12, 2024 | Messe München


Company Values

Applied Microspheres provides small polystyrene particles that are used as particle size standards and counting controls to validate and calibrate particle analyzers and flow cytometers. These particles are also used as reagents for a variety of diagnostic applications.

All technologies are supported by Applied Microspheres’ own product specialists and through close cooperation with suppliers, customers can count on optimal service, customer support and advice. This is achieved by efficient cooperation and division of tasks between product specialists and administrative employees in the office.

We strive for a high degree of flexibility in which quality and fast service are of paramount importance. Applied Microspheres’ main focus is delivering the highest quality of customer service and expertise. Therefore, Applied Microspheres distinguishes itself from other, often large, multinational operating groups that are present in the market.

Our expertise



Over the past decades, it has been common practice to validate and calibrate particle sizing and particle counting instruments with a standard that is traceable to standard reference materials from the National Institute of Standards and Technology (NIST) of the USA. With the ever increasing demand for instrument calibration and validation according to more internationally standardised procedures (ISO), Applied Microspheres has developed particle size standards and count controls that are not only NIST traceable, but also traceable to reference materials certified by an ISO 17025 accredited laboratory. Applied Microspheres’ particle size standards and count control product lines therefore meet the highest international metrological standard available.


The basis for the development of such standards is Applied Microspheres’ ability to produce large batches of (polymer) nano- and microspheres with very narrow size distributions. This expertise is also fundamental for the development of other products, such as zeta potential standards, multi-modal size standards, flow cytometry instrument controls and custom made instrument controls on OEM basis. Applied microspheres also offers a variety of (fluorescent) dyes that can be incorporated in the polymer matrix of their particles.


Technical support

Our skilled team of experts are standy to help and advice you.

ISO: 9001-2015 certified

Download our certificate in here in  English, German or Dutch.

Safe and fast delivery

We guarantee a safe, swift and fast delivery.

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Applied Microspheres

Nestléstr. 41
55120 Mainz

+49 6131 5540080

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Applied Microspheres